1. Synonyms for Suppository bases in Free Thesaurus. There seems to be little or no work done with such compounds as plastics, synthetic resins, and other similar condensation products. 1974;31(5):651-6. Measurement of gelation temperature. the release fo a drug from a fatty, lipophilic suppository base to the aqueous medium in the rectum depends on the _____ of the drug. 21 Specifications of suppository bases Examples of Macrogol bases: I II III IV Macrogol 400 Macrogol 1000 Macrogol 1540 Macrogol 4000 Macrogol 6000 Water - - - 33 47 20 - - 33 - 47 20 20 - 33 - 47 - - 75 - 25 - - By choosing a suitable combination a suppository base with the desired characteristics can be prepared. but soften, melt or dissolve readily at body temp; so … For adults, push it … Gently but firmly, push the suppository past the sphincter. Suppository Bases Sort by Sort by Show 24 36 48 View as from $32.00. Suppository bases usually used are theobroma oil, glycerinated gelatin, hydrogenated vegetable oils, mixtures of polyethylene glycols of various molecular weights, … V. Identification of products of ethionamide decay isolated from suppositories]. selection of suppository bases depends on. fatty bases. 2.3. It's a small, round or cone-shaped object that you put in your body, often into your bottom. Emulsified cocoa butter. -Emulsified Theobroma oil maybe used as base when large quantities of aqueous solutions are to be incorporated. (C) VAGINAL SUPPOSITORY It is in oviform shape. Insert the suppository into the rectum, narrow end first. bases also have low hydroxyl values (15 < 6 < 6) when compared to others, it is possible to explain the high release percentage of the active substance C31G from the vaginal suppositories prepared using these bases. Types of suppository bases by Hadeer Zedan 1. What are synonyms for Suppository bases? • A lipophilic drug that is distributed in a fatty suppository base in low concentration has less tendency to escape to the surrounding aqueous fluids than a hydrophilic substance in a fatty base. Identify the best product for your purpose and ask the related technical sheet to our team which will be pleased to help you. Witepsol bases: triglycerides of saturated fatty acids C12–C18, their melting ranges vary from 32 - 42 oC . 4 words related to suppository: medicament, medication, medicinal drug, medicine. water/base partition coefficient. A suppository can be introduced into any absorbent orifice of the body,such as the vagina. Suitable for both rectal and vaginal use. A problem that both compounders and patients face is the burdensome process of removing suppositories from outdated molds, whether they’re from bulky metal trays or the peel-away plastic suppository shells. It is contains the drugs which are used in treatment of the infections of female genitourinary tract and meant for contraception. University of Tennessee School of Pharmacy Memphis, Tenn. Graduate student in Hospital Pharmacy, University of Tennessee School of Pharmacy. Suppository bases play an important role in the release of medication they hold and the availability of the drug. Polyethylene Glycol Polymers have received much attention as suppository bases in recent years because they possess many desirable properties. Acta Pol Pharm. • Water soluble bases—for example, polyethylene glycols— that dissolve in the anorectal fluids release for absorption List and describe a variety of suppository bases. [Determination of the course of melting and solidification of suppository bases]. Table 1: Evaluation of the partitioning of C31G between various suppository bases/pH 8 buffer and chloroform/pH 8 buffer (n = 3) [Article in Italian] A suppository base must remain solid at room temp. -5% Glyceryl monostearate, 10% Lanette wax, 2_3% cetyl alcohol &4% bees wax is recommended for emulsified Theobroma oil. 1.2 Relationship between dossier specifications and the Pharmacopoeia We offer a wide range of suppository bases. The six general classes of suppository bases identified by the USP are described here. suppository bases in a sentence - Use "suppository bases" in a sentence 1. A suppository is a pill or medication that is inserted through the rectal area of the body. What is the main prereq for a suppository base? The influence of suppository bases upon the rectal absorption of acetylsalicylic acid. Absorbent orifice of the body and other similar condensation products Memphis, Tenn. Graduate student in Hospital Pharmacy, of... 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